מן הרשת 31.05.202017:07 FDA Approves Rucaparib for BRCA+ mCRPC The FDA has granted rucaparib (Rubraca) an accelerated approval for the treatment of adult patients with BRCA mutation (germline and/or somatic)–associated metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor–directed therapy and a taxane-based chemotherapy OncLive
מן הרשת 31.05.202017:05 Meta-Analysis Finds Adding ADT to EBRT Extends Survival in Localized Prostate Cancer External beam radiotherapy (EBRT) plus androgen deprivation therapy (ADT) showed superior overall survival (OS) compared with EBRT plus a brachytherapy boost (BT) in men with intermediate- and high-risk prostate cancer OncLive
מן הרשת 31.05.202016:08 NCCN Adds Rucaparib to Prostate Cancer Guidelines The National Comprehensive Cancer Network has updated its Clinical Practice Guidelines in Oncology for Prostate Cancer to include new recommendations for the PARP inhibitor rucaparib OncLive
מן הרשת 31.05.202016:07 Phase II TheraP Trial Shows Promise for LuPSMA in mCRPC Results from the TheraP trial, presented at the 2020 American Society of Clinical Oncology (ASCO) Virtual Scientific Program, found that in men with metastatic castration resistant prostate cancer (mCRPC) who progressed after treatment with docetaxel, 177Lu-PSMA-617 (LuPSMA) was more active than cabazitaxel OncLive
מן הרשת 31.05.202016:06 PD-L1 Expression on Tumour-Infiltrating Immune Cells Has No Prognostic Value in Renal Cell Carcinoma Programmed death ligand 1 (PD-L1) status on tumour-infiltrating immune cells was not an independent prognostic factor for patients with recurrent or metastatic renal cell carcinoma, according to a study presented at the 2020 American Urological Association (AUA) Virtual Meeting DG News
מן הרשת 31.05.202016:05 MR-Guided Focused Ultrasound Therapy Is Effective for Grade Group 2, 3 Prostate Cancer Magnetic resonance-guided focused ultrasound (MRgFUS) focal therapy using real-time MR thermometry is effective for grade group 2 and 3 prostate cancer, according to a study presented at the 2020 American Urological Association (AUA) Virtual Meeting DG News
מן הרשת 31.05.202016:04 Avelumab Extends Survival as Frontline Maintenance in Urothelial Carcinoma Adding avelumab (Bavencio) to best supportive care (BSC) improved the median overall survival (OS) by over 7 months in patients with locally advanced or metastatic urothelial carcinoma, according to findings from the phase 3 JAVELIN Bladder 100 study presented during the 2020 ASCO Virtual Scientific Program OncLive
מן הרשת 31.05.202013:25 Impact of timing of antibiotic use on clinical outcomes in patients with urothelial cancer treated with immune checkpoint inhibitors This updated analysis aims to addresses the question of timing; specifically, use of ABX in the 30-day window pre- or post- initiation of ICI treatment ASCO
מן הרשת 27.05.202012:05 FDA approves atezolizumab for first-line treatment of metastatic NSCLC with high PD-L1 expression On May 18, 2020, the Food and Drug Administration approved atezolizumab (TECENTRIQ®, Genentech Inc.) for the first-line treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have high PD-L1 expression FDA
מן הרשת 27.05.202012:03 FDA Approves Takeda’s ALUNBRIG® (brigatinib) as a First-Line Treatment Option for Rare Form of Lung Cancer − Long-Term Results from the Phase 3 ALTA 1L Trial Established ALUNBRIG as a Superior First-Line Treatment Compared to Crizotinib for People with ALK+ Metastatic NSCLC, Including those with Brain Metastases Business Wire
מן הרשת 27.05.202012:01 FDA Approves Opdivo® (nivolumab) + Yervoy® (ipilimumab) Combined with Limited Chemotherapy as First-Line Treatment U.S. Food and Drug Administration Approves Opdivo® (nivolumab) + Yervoy® (ipilimumab) Combined with Limited Chemotherapy as First-Line Treatment of Metastatic or Recurrent Non-Small Cell Lung Cancer BMS
מן הרשת 24.05.202012:09 FDA approves atezolizumab for first-line treatment of metastatic NSCLC with high PD-L1 expression the FDA also approved the VENTANA PD-L1 (SP142) Assay (Ventana Medical Systems, Inc.) as a companion diagnostic device for selecting patients with NSCLC for treatment with atezolizumab FDA
מן הרשת 18.05.202011:03 FDA Approves Opdivo-Yervoy Combination For Treatment of Metastatic NSCLC The Food and Drug Administration has approved the combination of Opdivo-Yervoy immunotherapy for the first-line treatment of patients with metastatic non-small cell lung cancer that do not have certain genomic tumor aberrations Cure
מן הרשת 14.05.202012:01 Onc Daily: Selpercatinib Approved, ASCO Goes Virtual Here are the most important stories that Medscape Oncology's editors picked for you to read today MedScape
מן הרשת 14.05.202011:59 Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer an open-label, multicentre, single-arm, phase 2 trial The Lancet Oncology
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